Founded in early 2005, StratiCELL is a leading company assisting the cosmetic, pharmaceutical and chemical industries to the safety and efficacy evaluation of their actives and products by means of in vitro models and methods in a GLP-compliant environment.

StratiCELL is a skin model manufacturer and a project-driven services provider for in vitro testing, with a particular emphasis on testing of skin care actives and products

Ageing


StratiCELL proposes different approaches to assess in vitro the activity of anti-ageing actives.


In Vitro biological endpoints for skin ageing.


In vitro induction of premature senescence in dermal fibroblasts (SIPS) and the corresponding study of senescence-related biomarkers

 

  • Senescence-Associated activity (commercial kit);
  • Cell proliferation;
  • ROS (Reactive oxygen species) measurement;
  • Activity of the stress protein p53;
  • DNA damage (CPD).
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    Ageing-linked modifications of proteins

    Measurement of collagen I production and metallo-protease activities

    Gene expression analysis of key genes involved in skin ageing and cellular senescence

    Ageing Skin

     

     

     

     

     

     

     

    Histological pictures comparing young to aged skins

    Our flyer on Dermato-Cosmetic Activity

     

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