Protection against urban pollution and smoke
Exposure of the skin to air pollutants is associated with skin aging, inflammatory or allergic skin conditions and cancer (Drakaki et al. 2014. Front. Environ. Sci.).
Among these effects, visible signs of aging are a major concern for many people (Global Industry Analysts reports an expected market value of $291.9 billion by 2015). Responding to the consumer expectations requires the identification and characterization of anti-pollution and detoxification skin cares.
Relying on our strong scientific expertise, StratiCELL commits to provide standardized and flexible in vitro assays assessing the “anti-pollution” effect of such skin care products. StratiCELL directly addresses the effects of real-life airborne pollutants using homogeneous and stable reference materials from diverse sources including urban dust, diesel exhaust particulates, and cigarette smoke extracts.
Our validated biomarkers include oxidative stress levels, enzymes of eicosanoids metabolism, detoxification enzymes, antioxidant enzymes, as well as skin-specific biomarkers associated with pollution-induced skin aging.
Our reference anti-pollution compounds include a panel of antioxidants as well as inducers of antioxidant and detoxification enzymes.
The assays are currently available on fibroblasts and keratinocytes and will be available on reconstituted human epidermal from (expected) February 2015.