In Vitro Skin Models
StratiCELL performs a panel of bioassays either on monolayer cultures (keratinocytes, fibroblasts, melanocytes, etc.), on human reconstituted epidermis or on ex vivo human skin, depending on the test product (formulated or water-soluble), on the selected endpoint(s), on the technique used, and on the sponsor expectations.
StratiCELL in vitro epidermal models demonstrate most features of the physiological function of the skin and are then relevant tools to profile safety, efficacy and mechanism of action of skin care actives and products after topical or systemic application.
The in vitro models are applied for RNA and protein extraction, gene expression analysis, immuno-fluorescence and immuno-histochemistry on tissues sections, histological assessment, ELISA, absorption assays etc.