Founded in early 2005, StratiCELL is a leading company assisting the cosmetic, pharmaceutical and chemical industries to the safety and efficacy evaluation of their actives and products by means of in vitro models and methods in a GLP-compliant environment.
StratiCELL is a skin model manufacturer and a project-driven services provider for in vitro testing, with a particular emphasis on testing of skin care actives and products
Specific Skin Related Thematic
StratiCELL predefined 4 TaqMan arrays focused on genes involved in a specific thematic. The StratiCELL predesigned TaqMan arrays focus on genes involved in skin ageing, in skin barrier and differentiation, in melanogenesis and sun protection or in wound healing and inflammation. Other arrays soon validated focus on anti-oxydant response, neurogenic inflammation, adipocyte biology and dermal extracellular matrix.
Skin Ageing. Intrinsic ageing of the skin occurs as a natural consequence of physiological changes over time, while extrinsic ageing includes exposure to external factor such as sunlight, pollution and other stresses. The StratiCELL predesigned TaqMan array focuses on genes involved in matrix synthesis and degradation, DNA repair, protein degradation and repair,...
Skin Barrier and Differentiation. The array is designed to study gene expression of key factors involved in barrier properties and epidermal differentiation. It focuses on genes involved in lipid/ceramid synthesis, hydratation, epidermal cohesion and desquamation.
Melanogenesis and Sun Protection. Regulation of melanin synthesis involves many factors. The StratiCELL predefined array allows to identify the mechanism involved in the modulation of skin pigmentation, by studying expression of key factors of melanogenesis. Furthermore photoprotection could be highlighted by changes in expression of genes involved in DNA repair or inflammation.
Skin Barrier and Differentiation. The array is designed to study gene expression of key factors involved in barrier properties and epidermal differentiation. It focuses on genes involved in lipid/ceramid synthesis, hydratation, epidermal cohesion and desquamation.
Melanogenesis and Sun Protection. Regulation of melanin synthesis involves many factors. The StratiCELL predefined array allows to identify the mechanism involved in the modulation of skin pigmentation, by studying expression of key factors of melanogenesis. Furthermore photoprotection could be highlighted by changes in expression of genes involved in DNA repair or inflammation.
Wound Healing and Inflammation. Target genes are involved in highly complex well-orchestrated processes leading to wound and burn healing such as cell proliferation, migration, matrix remodeling, angiogenesis and inflammation.
