StratiCELL® In Vitro Assays

StratiCELL® General

StratiCELL MEL/001 PDF Print E-mail

 

Applications of the StratiCELL® Reconstituted Epidermis with Melanocytes

  • In vitro de- and pro-pigmentation studies of skin care substances and products (systemic way);
  • Screening of molecular pathways involved in melanogenesis;
  • Gene expression profiling with proprietary TaqMan® arrays.

The StratiCELL® Reconstituted Epidermis with Melanocytes (MEL/001) is produced from human keratinocytes isolated from neonatal skin tissue from a pool of different donors, and from melanocytes from Black (MEL/001 DT) or Caucasian (MEL/001 LT) donors.
Cells are seeded on polycarbonate filters (standard size 0.63 cm2) and grown at the air-liquid interface in an appropriate cell culture medium. After two weeks of differentiation, a full pigmented epidermis is reconstituted.
For each batch of reconstituted pigmented human epidermis, the quality of the tissues is verified and detailed in a quality data sheet. 

StratiCELL has developed its proprietary reconstituted pigmented epidermis. The StratiCELL® Reconstituted Epidermis with Melanocytes (MEL/001) is commercially available. Their quality and high reproducibility make them ideal for use in alternatives to animal testing. 

Pigmented Reconstituted Epidermis

The StratiCELL® Reconstituted Epidermis with Melanocytes (MEL/001), melanin is visualized with a Fontana Masson staining on tissue sections

 

 StratiCELL® Reconstituted Human Epidermis is commercially available, please contact This e-mail address is being protected from spambots. You need JavaScript enabled to view it for prices and delivery dates.

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